Biological Network Representations and Databases
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چکیده
Transcriptional Regulatory Networks. In transcription regulatory networks the nodes represent transcription factors and genes while the links describe regulation-based interactions. Each link is directed, pointing from the transcription factor to the gene that it regulates. To compare the topological properties of transcription-regulatory networks to those of metabolic and protein-protein interaction networks, we have studied their undirected version where each directed link is replaced by an undirected one. The transcription network data of Escherichia coli has been reported in [2] and it is available from www.weizmann.ac.il/mcb/UriAlon. The transcription network data of Saccharomyces cerevisiae has been reported in [8], and it is available from http://www.weizmann.ac.il/mcb/UriAlon/Papers/networkMotifs/sma.html.
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